Chemist CV — page 1

Eleanor

Vance

Senior

Research

Chemist

C ONTAC T

+1 (510) 555-0192

evance

@

berkeley

.

edu

Berkeley

,

CA

94720

linkedin

.

com

/

in

/

evance

ED UC AT ION

UC

Berkeley

Ph

.

D

.

in

Organic

Chemistry

2018 – 2023

Massachusetts

Institute

of

Tech

.

B

.

Sc

.

in

Chemistry

2014 – 2018

C OR E

S KIL L S

Organic

Synthesis

Chromatography

(

HPLC

,

GC

-

MS

)

NMR

Spectroscopy

Computational

Chem

. (

DFT

,

MD

)

Python

for

Chemoinformatics

T EC H NIC AL

T OOL S

RDKit

PyTorch

AutoDock

AMBER

Gaussian

Schrödinger

ChemDraw

SciFinder

ELNs

L ANG UAG ES

English

(

Native

)

German

(

Professional

)

PR O F E S S I O N AL

S U M M AR Y

R

&

D

chemist

with

6+

years

of

experience

in

organic

synthesis

and

computational

drug

discovery

.

Proven

track

record

of

developing

scalable

synthetic

routes

for

complex

small

molecules

,

leading

cross

-

functional

teams

,

and

delivering

high

-

impact

publications

.

Passionate

about

leveraging

machine

learning

to

accelerate

reaction

discovery

and

optimization

.

E XPE R I E N C E

Postdoctoral

Researcher

—

UC

Berkeley

&

Lawrence

Livermore

National

Lab

2023 –

Present

Graduate

Research

Assistant

—

UC

Berkeley

2018 – 2023

Chemistry

Intern

(

Process

R

&

D

)

—

Merck

&

Co

.,

Rahway

,

NJ

Summer

2021

S E L E C T E D

PU B L I C AT I O N S

Vance

,

E

.,

Chen

,

T

., &

Hartwig

,

J

.

F

.

"

Scalable

Synthesis

of

Atropisomeric

Biaryls

via

Pd

-

Catalyzed

Dynamic

Kinetic

Developed

an

automated

high

-

throughput

screening

workflow

integrating

Python

scripting

and

robotic

liquid

handlers

,

screening

over

10,000

conditions

for

peptide

macrocyclization

.

–

Collaborated

with

a

team

of

6

researchers

to

elucidate

reaction

mechanisms

using

DFT

calculations

(

Gaussian

16)

and

kinetic

studies

.

–

Co

-

authored

4

peer

-

reviewed

publications

in

high

-

impact

journals

including

JACS

and

Angew

.

Chem

.

Int

.

Ed

.

–

Designed

and

synthesized

a

library

of

50+

novel

chiral

ligands

for

asymmetric

C

–

H

activation

catalysis

.

–

Achieved

a

30%

improvement

in

enantioselectivity

for

a

benchmark

C

–

H

arylation

reaction

through

rational

ligand

design

and

iteration

.

–

Mentored

3

undergraduate

research

students

,

resulting

in

2

co

-

authored

presentations

at

national

ACS

meetings

.

–

Optimized

the

synthesis

of

a

phase

II

clinical

candidate

,

reducing

the

step

count

from

12

to

8

and

increasing

overall

yield

by

22%.

–

Implemented

a

robust

HPLC

-

MS

purification

protocol

that

improved

product

purity

from

94%

to

99.5%.

–

Presented

findings

to

the

senior

leadership

team

,

leading

to

the

adoption

of

the

new

route

for

scale

-

up

.

–

1 / 2

Chemist CV — page 2

Mandarin

(

Conversational

)

Resolution

."

J

.

Am

.

Chem

.

Soc

. 2025, 147, 1234–1245.

Vance

,

E

.,

Lee

,

J

. &

Sigman

,

M

.

S

.

"

Ligand

-

Enabled

C

–

H

Alkylation

of

Heterocycles

with

High

Regioselectivity

."

Angew

.

Chem

.

Int

.

Ed

. 2024, 63,

e

202318934.

Vance

,

E

. &

Hartwig

,

J

.

F

.

"

Palladium

-

Catalyzed

Dearomative

Cyclization

of

Indoles

."

Chem

.

Sci

. 2023, 14, 7894–7902.

Miller

,

A

.,

Vance

,

E

., &

Toste

,

F

.

D

.

"

Gold

-

Catalyzed

Enyne

Cycloisomerization

:

A

Computational

and

Experimental

Study

."

ACS

Catal

. 2022, 12, 4567–4578.

H O N O R S

&

AWAR DS

NSF

Graduate

Research

Fellowship

Program

(

GRFP

)

2019

ACS

Division

of

Organic

Chemistry

Fellowship

2022

Outstanding

Graduate

Student

Instructor

Award

,

UC

Berkeley

2021

MIT

John

C

.

Bailar

Medal

for

Excellence

in

Undergraduate

Research

2018

2 / 2

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